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1

Control of Cardiac Rate by “Funny” Channels in Health and Disease

Andrea Barbuti, Dario DiFrancesco

Journal:

Annals of the New York Academy of Sciences

Year:

2008

Language:

english

File:

PDF, 728 KB

english, 2008

2

Action of serotonin on the hyperpolarization-activated cation current (Ih) in rat CA1 hippocampal neurons

Sonia Gasparini, Dario DiFrancesco

Journal:

European Journal of Neuroscience

Year:

1999

Language:

english

File:

PDF, 489 KB

english, 1999

3

Erratum to: Intracellular Ca modulates K-inward rectification in cardiac myocytes

Michele Mazzanti, Dario DiFrancesco

Journal:

Pflügers Archiv European Journal of Physiology

Year:

1989

Language:

english

File:

PDF, 69 KB

english, 1989

4

Acetylcholine inhibits activation of the cardiac hyperpolarizing-activated current,if

Dario DiFrancesco, Cinzia Tromba

Journal:

Pflügers Archiv European Journal of Physiology

Year:

1987

Language:

english

File:

PDF, 408 KB

english, 1987

5

Intracellular Ca modulates K-inward rectification in cardiac myocytes

Michele Mazzanti, Dario DiFrancesco

Journal:

Pflügers Archiv European Journal of Physiology

Year:

1989

Language:

english

File:

PDF, 271 KB

english, 1989

6

Some properties of the UL-FS 49 block of the hyperpolarization-activated current (if) in sino-atrial node myocytes

Dario DiFrancesco

Journal:

Pflügers Archiv European Journal of Physiology

Year:

1994

Language:

english

File:

PDF, 763 KB

english, 1994

7

HCN-related channelopathies

Mirko Baruscotti, Georgia Bottelli, Raffaella Milanesi, Jacopo C. DiFrancesco, Dario DiFrancesco

Journal:

Pflügers Archiv European Journal of Physiology

Year:

2010

Language:

english

File:

PDF, 508 KB

english, 2010

8

Kinetic and ionic properties of the human HCN2 pacemaker channel

Anna Moroni, Andrea Barbuti, Claudia Altomare, Carlo Viscomi, Julie Morgan, Mirko Baruscotti, Dario DiFrancesco

Journal:

Pflügers Archiv European Journal of Physiology

Year:

2000

Language:

english

File:

PDF, 116 KB

english, 2000

9

Single-channel properties of the sinoatrial node Na+current in the newborn rabbit

Mirko Baruscotti, Dario DiFrancesco, Richard B. Robinson

Journal:

Pflügers Archiv European Journal of Physiology

Year:

2001

Language:

english

File:

PDF, 80 KB

english, 2001

10

Dual allosteric modulation of pacemaker (f) channels by cAMP and voltage in rabbit SA node

Dario DiFrancesco

Journal:

The Journal of Physiology

Year:

1999

Language:

english

File:

PDF, 392 KB

english, 1999

11

Cesium and the Pacemaker Current

Dario DiFrancesco

Journal:

Journal of Cardiovascular Electrophysiology

Year:

1995

Language:

english

File:

PDF, 212 KB

english, 1995

12

The Pacemaker Current: From Basics to the Clinics

ANDREA BARBUTI, MIRKO BARUSCOTTI, DARIO DIFRANCESCO

Journal:

Journal of Cardiovascular Electrophysiology

Year:

2007

Language:

english

File:

PDF, 120 KB

english, 2007

13

Characterization of single pacemaker channels in cardiac sino-atrial node cells

DiFrancesco, Dario

Journal:

Year:

1986

File:

PDF, 433 KB

1986

14

Direct activation of cardiac pacemaker channels by intracellular cyclic AMP

DiFrancesco, Dario, Tortora, Paolo

Journal:

Year:

1991

File:

PDF, 352 KB

1991

15

Effects of dronedarone on Acetylcholine-activated current in rabbit SAN cells

Claudia Altomare, Andrea Barbuti, Carlo Viscomi, Mirko Baruscotti, Dario DiFrancesco

Journal:

British Journal of Pharmacology

Year:

2000

Language:

english

File:

PDF, 140 KB

english, 2000

16

Functional characterisation and subcellular localisation of HCN1 channels in rabbit retinal rod photoreceptors

Gian Carlo Demontis, Anna Moroni, Biagio Gravante, Claudia Altomare, Biancamaria Longoni, Luigi Cervetto, Dario DiFrancesco

Journal:

The Journal of Physiology

Year:

2002

Language:

english

File:

PDF, 371 KB

english, 2002

17

Heteromeric HCN1–HCN4 Channels: A Comparison with Native Pacemaker Channels from the Rabbit Sinoatrial Node

Claudia Altomare, Benedetta Terragni, Chiara Brioschi, Raffaella Milanesi, Cinzia Pagliuca, Carlo Viscomi, Anna Moroni, Mirko Baruscotti, Dario DiFrancesco

Journal:

The Journal of Physiology

Year:

2003

Language:

english

File:

PDF, 391 KB

english, 2003

18

Pacemaker Channels

MIRKO BARUSCOTTI, DARIO DIFRANCESCO

Journal:

Annals of the New York Academy of Sciences

Year:

2004

File:

PDF, 3.46 MB

2004

19

Functional comparison of HCN isoforms expressed in ventricular and HEK 293 cells

Bucchi, Annalisa, DiFrancesco, Dario, Robinson, Richard, Qu, Jihong, Altomare, Claudia

Journal:

Pflügers Archiv European Journal of Physiology

Year:

2002

Language:

english

File:

PDF, 87 KB

english, 2002

20

Generation and control of cardiac pacing the pacemaker current

Dario DiFrancesco

Journal:

Trends in Cardiovascular Medicine

Year:

1991

Language:

english

File:

PDF, 927 KB

english, 1991

21

Serious workings of the funny current

Dario DiFrancesco

Journal:

Progress in Biophysics and Molecular Biology

Year:

2006

Language:

english

File:

PDF, 305 KB

english, 2006

22

Physiology and pharmacology of the cardiac pacemaker (“funny”) current

Mirko Baruscotti, Annalisa Bucchi, Dario DiFrancesco

Journal:

Pharmacology & Therapeutics

Year:

2005

Language:

english

File:

PDF, 1.08 MB

english, 2005

23

Multinucleated giant cells with an osteoclast phenotype derived from caprine peripheral blood mononuclear cells

Giuliano Pisoni, Patrizia D’Amelio, Francesca Sassi, Giovanni Manarolla, Licia Scaccabarozzi, Clara Locatelli, Nausicaa Mazzocchi, Mirko Baruscotti, Dario DiFrancesco, Paolo Moroni

Journal:

The Veterinary Journal

Year:

2011

Language:

english

File:

PDF, 584 KB

english, 2011

24

Heart rate reduction via selective ‘funny’ channel blockers

Annalisa Bucchi, Andrea Barbuti, Mirko Baruscotti, Dario DiFrancesco

Journal:

Current Opinion in Pharmacology

Year:

2007

Language:

english

File:

PDF, 311 KB

english, 2007

25

Localization of f-channels to caveolae mediates specific β2-adrenergic receptor modulation of rate in sinoatrial myocytes

Andrea Barbuti, Benedetta Terragni, Chiara Brioschi, Dario DiFrancesco

Journal:

Journal of Molecular and Cellular Cardiology

Year:

2007

Language:

english

File:

PDF, 653 KB

english, 2007

26

Autonomic rate modulation in san cells involves changes in diastolic depolarization and the i(f) current

Mirko Baruscotti, Annalisa Bucchi, Richard B. Robinson, Dario DiFrancesco

Journal:

Journal of Molecular and Cellular Cardiology

Year:

2007

Language:

english

File:

PDF, 54 KB

english, 2007

27

Modulation of rate by autonomic agonists in SAN cells involves changes in diastolic depolarization and the pacemaker current

Annalisa Bucchi, Mirko Baruscotti, Richard B. Robinson, Dario DiFrancesco

Journal:

Journal of Molecular and Cellular Cardiology

Year:

2007

Language:

english

File:

PDF, 884 KB

english, 2007

28

Molecular composition and functional properties of f-channels in murine embryonic stem cell-derived pacemaker cells

Andrea Barbuti, Alessia Crespi, Daniela Capilupo, Nausicaa Mazzocchi, Mirko Baruscotti, Dario DiFrancesco

Journal:

Journal of Molecular and Cellular Cardiology

Year:

2009

Language:

english

File:

PDF, 1.39 MB

english, 2009

29

What keeps us ticking: a funny current, a calcium clock, or both?

Edward G. Lakatta, Dario DiFrancesco

Journal:

Journal of Molecular and Cellular Cardiology

Year:

2009

Language:

english

File:

PDF, 788 KB

english, 2009

30

Distribution of the pacemaker HCN4 channel mRNA and protein in the rabbit sinoatrial node

Chiara Brioschi, Stefano Micheloni, James O. Tellez, Giuliano Pisoni, Renato Longhi, Paolo Moroni, Rudi Billeter, Andrea Barbuti, Halina Dobrzynski, Mark R. Boyett, Dario DiFrancesco, Mirko Baruscotti

Journal:

Journal of Molecular and Cellular Cardiology

Year:

2009

Language:

english

File:

PDF, 1.36 MB

english, 2009

31

Mesoangioblasts from ventricular vessels can differentiate in vitro into cardiac myocytes with sinoatrial-like properties

Andrea Barbuti, Beatriz G. Galvez, Alessia Crespi, Angela Scavone, Mirko Baruscotti, Chiara Brioschi, Giulio Cossu, Dario DiFrancesco

Journal:

Journal of Molecular and Cellular Cardiology

Year:

2010

Language:

english

File:

PDF, 1.14 MB

english, 2010

32

Considerations on the size of currents required for pacemaking

Dario DiFrancesco

Journal:

Journal of Molecular and Cellular Cardiology

Year:

2010

Language:

english

File:

PDF, 117 KB

english, 2010

33

A caveolin-binding domain in the HCN4 channels mediates functional interaction with caveolin proteins

Andrea Barbuti, Angela Scavone, Nausicaa Mazzocchi, Benedetta Terragni, Mirko Baruscotti, Dario DiFrancesco

Journal:

Journal of Molecular and Cellular Cardiology

Year:

2012

Language:

english

File:

PDF, 1.17 MB

english, 2012

34

The short N-terminus is required for functional expression of the virus-encoded miniature K+ channel Kcv

Anna Moroni, Carlo Viscomi, Vanessa Sangiorgio, Cinzia Pagliuca, Tobias Meckel, Ferenc Horvath, Sabrina Gazzarrini, Paola Valbuzzi, James L Van Etten, Dario DiFrancesco, Gerhard Thiel

Journal:

Year:

2002

Language:

english

File:

PDF, 415 KB

english, 2002

35

The viral potassium channel Kcv: structural and functional features

Sabrina Gazzarrini, Maria Severino, Mara Lombardi, Marzia Morandi, Dario DiFrancesco, James L Van Etten, Gerhard Thiel, Anna Moroni

Journal:

Year:

2003

Language:

english

File:

PDF, 246 KB

english, 2003

36

If-dependent modulation of pacemaker rate mediated by cAMP in the presence of ryanodine in rabbit sino-atrial node cells

Annalisa Bucchi, Mirko Baruscotti, Richard B. Robinson, Dario DiFrancesco

Journal:

Journal of Molecular and Cellular Cardiology

Year:

2003

Language:

english

File:

PDF, 224 KB

english, 2003

37

An updated computational model of rabbit sinoatrial action potential to investigate the mechanisms of heart rate modulation

Stefano Severi, Matteo Fantini, Lara A. Charawi, Dario DiFrancesco

Journal:

The Journal of Physiology

Year:

2012

Language:

english

File:

PDF, 1.78 MB

english, 2012

38

The cardiac hyperpolarizing-activated current, if. origins and developments

Dario DiFrancesco

Journal:

Progress in Biophysics and Molecular Biology

Year:

1985

Language:

english

File:

PDF, 1.47 MB

english, 1985

39

Differential effects of ACH on cardiac pacemaker cells

Dario DiFrancesco, Pierre Ducouret, Richard Robinson

Journal:

Trends in Neurosciences

Year:

1992

Language:

english

File:

PDF, 142 KB

english, 1992

40

Mutation in Pore Domain Uncovers Cation- and Voltage-Sensitive Recovery from Inactivation in KAT1 Channel

Moroni, Anna, Gazzarrini, Sabrina, Cerana, Raffaella, Colombo, Roberta, Sutter, Jens-Uwe, DiFrancesco, Dario, Gradmann, Dietrich, Thiel, Gerhard

Journal:

Biophysical Journal

Year:

2000

Language:

english

File:

PDF, 169 KB

english, 2000

41

Funny channels in the control of cardiac rhythm and mode of action of selective blockers

Dario DiFrancesco

Journal:

Pharmacological Research

Year:

2006

Language:

english

File:

PDF, 307 KB

english, 2006

42

Heart Rate Lowering by Specific and SelectiveIfCurrent Inhibition with Ivabradine

Dario DiFrancesco, Professor John A. Camm

Journal:

Year:

2004

Language:

english

File:

PDF, 276 KB

english, 2004

43

The Funny Current

DiFrancesco, Dario, Borer, Jeffrey S

Journal:

Year:

2007

Language:

english

File:

PDF, 170 KB

english, 2007

44

Handbook of Membrane Channels || Hyperpolarization-Activated (if) Current in Heart

DiFRANCESCO, DARIO

Year:

1994

Language:

english

File:

PDF, 892 KB

english, 1994

45

Cyclic dinucleotides bind the C-linker of HCN4 to control channel cAMP responsiveness

Lolicato, Marco, Bucchi, Annalisa, Arrigoni, Cristina, Zucca, Stefano, Nardini, Marco, Schroeder, Indra, Simmons, Katie, Aquila, Marco, DiFrancesco, Dario, Bolognesi, Martino, Schwede, Frank, Kashin,

Journal:

Nature Chemical Biology

Year:

2014

Language:

english

File:

PDF, 1.33 MB

english, 2014

46

A Validated Computational Model of Cardiac Pacemaking: Mechanisms of Physiological and Pharmacological Rate Modulation

Severi, Stefano, Fantini, Matteo, Ravagli, Enrico, Charawi, Lara, DiFrancesco, Dario

Journal:

Biophysical Journal

Year:

2012

Language:

english

File:

PDF, 158 KB

english, 2012

47

The funny current has a major pacemaking role in the sinus node

DiFrancesco, Dario, Noble, Denis

Journal:

Year:

2012

Language:

english

File:

PDF, 175 KB

english, 2012

48

How “Funny” is the Cardiac Pacemaking? a Quantitative Analysis Based on Dynamic Clamp Recordings

Ravagli, Enrico, Bucchi, Annalisa, Bartolucci, Chiara, Baruscotti, Mirko, DiFrancesco, Dario, Severi, Stefano

Journal:

Biophysical Journal

Year:

2014

Language:

english

File:

PDF, 46 KB

english, 2014

49

Funny channel-based pacemaking

DiFrancesco, Dario

Journal:

Year:

2010

Language:

english

File:

PDF, 406 KB

english, 2010

50

Rebuttal: “The funny current in the context of the coupled clock pacemaker cell system”

DiFrancesco, Dario, Noble, Denis

Journal:

Year:

2012

Language:

english

File:

PDF, 444 KB

english, 2012

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